Both CB1 and CB2 helps your ECs to regulate your inflammation levels, pain levels, immune functions, sleep, digestion, appetite, memory, mood, and other functions. It makes an impact exactly where needed to create balance and homeostasis. Once they achieve balance in your body, enzymes break them down so they don’t cause any damage or disrupt the balance in the opposite direction.
Homeostasis is non-negotiable for your health. When your ECS isn’t working properly it may lead to a variety of problems inside your body. Clinical encodcannabionoid deficiency (CECD) refers to a variety of conditions related to an ECS that is not working optimally. CECD conditions may include fibromyalgia, migraines, irritable bowel syndrome (IBD), and other health issues that may cause pain in your body.
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
CBD affects the endocannabinoid system, which has cannabinoid receptors throughout the human body. That’s one of the major reasons why CBD’s therapeutic properties include pain relief. The cannabinoid receptors are connected to the human nervous system.  CBD affects some of them (not CB1 and CB2 which are activated by THC) and a  neural connection is triggered in the brain.
CBD oil is not legal everywhere. It is banned/restricted by countries such as UAE, Dubai, and Saudi Arabia. Although CBD oil is illegal in many of the US states too, some have legalized its use for medicinal purposes. While the number would be ever-changing, as of 2016 there are 17 states in the US which have legalized the use of low THC, high CBD products for medical reasons in limited situations. These states include Alabama, Georgia, Iowa, Kentucky, Florida, Mississippi, Louisiana, Missouri, North Carolina, Oklahoma, South Carolina, Wisconsin, Wyoming, Tennessee, Texas, Utah, and Virginia. It is advisable to consult your local health specialist before use.
We have receptors for cannabinoids in the whole body, but the first type (CB1) are very dense in the pain pathways of the brain, spine, and nerves. The second type (CB2) are more important for the immune system but is also involved in inflammation. By gently acting on both pathways, our internal cannabinoids and CBD can balance both pain and inflammation [64].
“Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
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