Pure CBD Vapors was here before the CBD boom, and our founding principles of transparency and trust have made us an online fan-favorite in the CBD community. Shop with us and enjoy what thousands of repeat customers have come to expect from Pure CBD: high quality products, fair prices, stellar customer service, and a huge selection of the industry’s most exciting items.
Since 2014, NuLeaf Naturals – our Editor’s Pick – has been committed to creating high-quality CBD oil products. As one of the oldest and most reviewed companies in the industry, NuLeaf Naturals has established themselves as a trustworthy CBD manufacturer. All of their products are tested by third party labs and their cannabinoid profile is impressive. They offer a unique range of concentrations for their organic CBD products ranging from 240mg to 4,850mg.
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‘In the 1940s and early 1950s, further studies showed inactivation of diverse bacteria, influenza virus, and Penicillium chrysogenum (previously P. notatum) mold fungus using various glycols, principally propylene glycol and triethylene glycol.[6] In principle, these chemical substances are ideal air disinfectants because they have both high lethality to microorganisms and low mammalian toxicity.’

ReLive Full Spectrum Hemp Oil capsules carry 600mg of hemp oil in every bottle, with 20mg of oil in each capsule. ReLive is a GMP certified manufacturer, and the product contains all-natural ingredients. Each bottle carries a 30-day supply of capsules with the recommended dosage. Despite the name, this product contains only hemp seed oil and not full spectrum hemp oil, which means there are no CBD cannabinoids present. Even so, this product is excellent for those who wish to use hemp oil as a vitamin supplement full of Omega-3 and Omega-6, rather than a means to manage health-related symptoms.
Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.

Since 2014, NuLeaf Naturals – our Editor’s Pick – has been committed to creating high-quality CBD oil products. As one of the oldest and most reviewed companies in the industry, NuLeaf Naturals has established themselves as a trustworthy CBD manufacturer. All of their products are tested by third party labs and their cannabinoid profile is impressive. They offer a unique range of concentrations for their organic CBD products ranging from 240mg to 4,850mg.
iVitamins Premium Hemp Oil 1000mg contains both full spectrum hemp oil (which does contain CBD) and high-quality hemp seed oil in every bottle. Other all-organic ingredients include orange oil and stevia for flavoring, as well as grape seed oil. As a manufacturer, iVitamins is GMP certified. At an affordable price, this USA-made product may be perfect for those looking to introduce hemp oil into their daily regimen for the first time.
At this time, there does seem to be a growing body of basic pharmacologic data suggesting there may be a role for CBD, especially in the treatment of refractory epilepsy. However, given the lack of well-controlled trials, we must also ask if we are getting ahead of ourselves. Clearly, this is an emotionally and politically charged issue. If this were any other uninvestigated pharmaceutical compound, would we feel as compelled to make the agent widely available before statistically valid class 1 evidence was available for review? Until data from well-designed clinical trials are available and reliable, and standardized CBD products that are produced using GMP are available, caution must be exercised in any consideration of using CBD for the treatment of epilepsy. In the meantime, based upon promising preliminary data, further clinical research should be wholeheartedly pursued.

CBD is well tolerated in humans with doses up to 600 mg not resulting in psychotic symptoms (15). In the few small placebo-controlled studies performed, no significant CNS effects were noted. Oral CBD undergoes extensive first-pass metabolism via CYP3A4, with a bioavailability of 6%. Following single doses in humans, the half-life of CBD when taken orally is about 1 to 2 days.1 In vitro studies have shown that CBD is a potent inhibitor of multiple CYP isozymes, including CYP 2C and CYP3A (16, 17). Whether these in vitro observations are relevant at plasma concentrations likely to be seen in patients is unclear. In addition, given its metabolism via CYP3A4, clinical trials of CBD in patients receiving enzyme-inducing AEDs, such as carbamazepine or phenytoin, will require detailed pharmacokinetic studies.


Serenity Hemp Oil is certified organic, made in the USA, and carries the most positive reviews by consumers, setting it at our #1 spot for CBD / hemp oils on Amazon. Larger than most products available on amazon, Serenity Hemp Oil comes in a 4 fl. oz. bottle, and with recommended dosage, it will yield up to 120 days of use. Flavors are orange and peppermint, with lots of positive feedback on both flavors. Manufactured by Serenity Remedies, this product is derived from all-natural methods and contains all-natural ingredients. A portion of proceeds from Serenity Remedies goes to charity as well, assisting patients in obtaining high-cost CBD oil to aid in their health problems.
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